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[Abstract]2024 Jan;38(1):e23542

1 Introduction Vitamins of the B complex comprise a group of eight water-soluble vitamins that play a crucial role in maintaining optimal neurological function, such as energy production, DNA/RNA synthesis/repair, genomic and non-genomic methylation, and synthesis of neurochemicals ( Figures 1 , 2 ) ( Figure 1 Figure 2 Thiamine (B1) deficiency is often associated with beriberi, a syndrome mainly characterized by polyneuritis and/or cardiovascular symptoms ( In conclusion, B vitamins are essential for both catabolic and anabolic metabolism functioning as coenzymes in numerous processes vital to cellular physiology, including brain and nervous system activities ( Table 1 )

The good news is that most reactions are mild and short-lived: tenderness, a small bruise, or a bit of redness usually settle within 24 to 72 hours

This route may be considered in some clinical situations where oral therapy is complicated