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2022 Sep 28;14(9):e29696

High pH fractionation- TMT labeled, combined, and dried samples were resuspended in 300 L of Buffer A (5% v/v MeCN, 95% v/v H 2 O, 0.1% v/v formic acid) and fractionated by centrifugation using a peptide desalting column (Pierce, #89852)

In particular, the treatment with the enzyme of glutathione-metal conjugates isolated from the bile of experimentally intoxicated animals was used as an evidence of their possible connectivity in the earlier toxicological studies [43,47]

Several hypertension models suggest a close association between decreased NO bioavailability and increased oxidative stress and hypertension