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Oxidative stress occurs when there is an imbalance between the amount of free radicals and our ability to fight them off, and increases as we age

Study results showed the NTCI peptide drastically reduced itching, inflammation, and open skin lesions without apparent toxicity

Preclinical studies have shown that PD-1/PD-L1 blockade can mobilize monocyte-derived macrophages, enabling their infiltration into the brain to reduce pathology and combat cognitive decline in 5XFAD AD mice [350, 351]

It is associated with genetic mutations (e.g., filaggrin), environmental factors, skin barrier dysfunction, and transepidermal water loss [5, 25]