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Laboratory studies have examined GHK-Cu's effects on the expression of growth factors including basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) in cell culture models, particularly at concentrations around 1 nM

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This is particularly relevant when LDL-C is low, but triglycerides remain elevated, when metabolic syndrome is present, or when residual ASCVD risk appears disproportionate to LDL-C

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