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The possible sources are: (1) decreased expression and activity of cellular antioxidant systems (discussed above), or (2) increased production of ROS through major sources, such as mitochondria, that overcome the cellular antioxidant capacity, or (3) both
Plant-based foods like cereals and some vegetables and fruits also contain selenium, with amounts varying based on soil selenium content and other factors (including soil pH and the amount of organic matter in the soil) [55]
The 2016 Draelos study in Journal of Drugs in Dermatology compared a crosslinked HA serum with recombinant EGF against a fibroblast-conditioned media serum and documented meaningful improvements in skin appearance and texture [31]
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