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Simultaneously, LPS significantly inhibits the expression of hepatic SIRT1 and FOXA2, which downregulates the NFE2L2/HMOX1 antioxidant signaling axis, diminishes the activity of key antioxidant enzymes (e.g., CAT, SOD, and GPX1), and upregulates autophagy-related proteins such as MAP1LC3-II and ATG5 171

Routes of Drug Administration Chapter 6 48.Giovannitti JA, Trapp LD (1991) Adult sedation: oral, rectal, IM, IV

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Peptide therapy vs IV drips and other treatments Peptide therapy vs IV drip therapy -peptides are typically injected or applied topically and work over time