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Leptin administration has successfully treated hyperphagia and obesity in humans and rodents with leptin deficiency [26]

Pituitary Tumor complications: In rare cases where a pituitary tumor (like a prolactinoma) is the cause, complications can include headaches and vision problems if the tumor grows large enough to press on surrounding structures

They are now undergoing extensive research with human trials for potential use as part of the healthy aging process (Guarente et al 2024)

Carnosine for glycation protection in diabetic retinopathy Carnosine properties: Dipeptide (beta-alanyl-L-histidine) preventing protein glycation, breaking existing advanced glycation end-products (AGEs), protecting against diabetic complications including retinopathy