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doi: 10.1007/s00417-021-05377-9 349 HuangYWuYZhangSLuYWangYLiuXet al

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However, the application of Bacillus metabolites in heavy metal remediation faces challenges, including prolonged treatment durations, the necessity for stable environmental conditions, and specific nutrient requirements.This review summarizes recent research on the effects of heavy metal exposure on the metabolic pathways and metabolites of Bacillus spp., elucidates their role in influencing metal bioavailability and chemical transformations, and explores innovative strategies to enhance the stability of Bacillus -mediated heavy metal remediation