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Metabolic unpredictability: Simultaneously altering multiple metabolic pathways incretin signalling, glucagon activity, and NAD+ metabolism without clinical oversight introduces unpredictable physiological consequences

doi: 10.3389/fpsyt.2025.1569826 Received 01 February 2025 Accepted 16 July 2025 Published 19 August 2025 Volume 16 - 2025 Edited by Sandra Moreno, Roma Tre University, Italy Reviewed by Poonam Chanderlal Sharma, University of Mississippi Medical Center, United States Ashish Patil, Roche, United States Updates Copyright 2025 Han, Almeida, Anand, Salloum, Kanaan, Gadad and Daher

TB-500, a fragment of thymosin beta-4, binds actin and promotes the cell migration and angiogenesis that healing depends on