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Safety Takeaway: While the evidence from controlled human trials suggests a manageable adverse event profile, the products full extent of long-term safety, especially regarding chronic and rare side effects, remains undetermined until the completion of ongoing large-scale clinical programs and subsequent regulatory review and approval

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Sun L, Guo Z, Qin W et al (2026) Cationic hydrogel with sustained lubrication and anti-calcification for osteoarthritis therapy

However, it also plays a role in cancer where it supplies tumors with the oxygen and nutrients needed to grow and spread