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SSZ mildly induced cell death and lipid peroxidation in A549, H838, H460, and H2122 cells, but it caused a significantly greater percentage of cell death and lipid peroxidation in LDHB KD cells ( Figure 2f, 2g, Supplementary Figure 4k )

Knockdown of Gal-1 in CAFs reduced the expression of monocyte chemoattractant protein-1 (MCP-1) and inhibited the progression of OSCC in vivo [172]

Conflict of interest PS and ST have patents pertaining to MS

Another investigation demonstrated the anticolitic effect of carvacol is associated with the protection of mucosal barrier through reducing translocation of NF-B pathway and inhibiting TLR4 receptor activation pathway in DSS induced colitis model