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It is not manufactured or labeled for human cosmetic use, clinical application, or any consumer-facing formulation, and it must not be applied, injected, or otherwise administered to humans.

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Thus, with pathologic HNE concentrations (10M and higher) for rat GCLC, ERK activation was required for the HNE-mediated induction but for human GCLC, JNK activation was essential and Nrf2 was not required (Iles and Liu, 2005)

The study found that subcutaneous administration of CJC-1295 led to dose-dependent and sustained increases in GH and IGF-I levels