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Leveraging self-reported symptoms as listed under the World Health Organizations International Classifications of Diseases and Injuries (ICD) 10th Revision 5 or the American Psychiatric Associations Diagnostic and Statistical Manual Fifth Edition (DSM-5) 6 to diagnose nicotine dependence, researchers have traditionally relied on self-report measures to assess perceived dependence on TNPs

In general, experiencing fever, chills and headaches are uncommon

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That's why so many people turn back to nicotine when they're stressed - their mind and body don't know how to deal with even minor amounts of stress without it