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Some trials reported enhanced physical performance (17) (20) , and improved aerobic capacity and exercise tolerance (32) whereas others yielded mixed results (37) (38) (39)

Excessive excitatory neurotransmitter glutamate in neuronal synapses, disruption of homeostasis in the glutamate-glutamine cycle in astrocytes, and dysfunction of ATP-dependent energy supply by anaerobic glycolysis of glucose

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