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Additionally, a prospective cohort study reported a HR of 1.17 (95% CI: 0.831.66), while a separate cohort study identified an IRR of 1.57 (95% CI: 1.152.13), further supporting the association between e-cigarette use and COPD risk

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Although both groups had similar frequencies of chronic obstructive pulmonary disease (COPD) exacerbations worsening of the condition throughout the study, menthol smokers had a higher frequency of severe exacerbations at 0.22 per year, compared to 0.18 per year for regular cigarette smokers

A pack of cigarettes cost just 25 cents in the 1950s