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29 A statistical analysis of 17 randomized controlled trials that included a total of over 1,000 participants found that intake of probiotics, prebiotics (partially or completely indigestible carbohydrates that enhance growth of beneficial gut bacteria), or synbiotics (combinations of probiotics and prebiotics) was of benefit for metabolic aspects of PCOS

Am J Kidney Dis 32:853906

The agency has not evaluated whether the unapproved products subject to the warning letters announced today are effective for their intended use, what the proper dosage might be, how they could interact with FDA-approved drugs or other substances, or whether they have dangerous side effects or other safety concerns