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Moreover, at moderate levels, ROS oxidatively modifies KEAP1, thereby activating the NRF2 pathway, which induces the transcription of antioxidant genes such as SOD2, GPX1, and HO-1, establishing a defense against oxidative stress in granulosa cells [236]

San-Milln I, Julian CG, Matarazzo C, Martinez J, Brooks GA

Studies suggest that Pal-GHK may potentially possess anti-RCS properties, particularly against radicals like acrolein, malondialdehyde, and 4-hydroxynoneal, and thus reduce the risk of protein glycation of skin cell structures and ECM structures

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