BPC-157 Mechanisms BPC-157 exerts its effects through upregulation of vascular endothelial growth factor (VEGF), promoting angiogenesis and new blood vessel formation
Beyond POTS, autonomic dysfunction in long COVID can present as: Dysregulated sweating Impaired gastrointestinal muscle contractions, causing constipation, pain, nausea, or weight loss Temperature dysregulation An exaggerated fight-or-flight response The vagus nerve within this systemthe primary parasympathetic nerve connecting the brain to the gut, heart, and lungsappears to be particularly vulnerable to COVID-19-related damage, with implications for heart rate variability, gut function, and the inflammatory regulatory role the vagus nerve normally performs
JAMA Neurol 2021;78(10):11871196
Although no causation has been established for ME/CFS, as the knowledge around the disease expands, so will the potential treatment avenues