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Liver biopsy findings may support a diagnosis of PSC, but they are often nondiagnostic, and liver biopsy is rarely necessary if a patient has characteristic findings with cholangiography

The idea behind these shots is that they help the body break down fat more efficiently, boost metabolism, and increase energy levels, potentially aiding in weight loss

If sublingual B12 doesn't improve your symptoms after a few months, switch to B12 injections since cellular absorption is superior

There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision