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In total, we generated six LMNA transgenic zebrafish lines: LMNA (WT), 3 novel and 2 known pathogenic mutant lines, including LMNA (L35P), LMNA (E358K), LMNA (R453W), LMNA (W520G), and LMNA (A539V), and which were validated by fin-clip, and the presence of the intended mutations was confirmed by comparing them to the LMNA (WT) sequence (Fig

This means that things that might have caused a slight temperature rise that stayed within the TNZ before, suddenly are enough to push your body out of the zone and cause sweating [4]

PMID: 26220150

Therefore, simply reducing iron exposure is not an effective method for managing CKD, and maintaining iron balance should be approached cautiously