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Using the Broad Institutes Connectivity Map, the group reported that GHK modulates the expression of a very large number of human genes, on the order of thousands, and tends to shift pathological or aged expression patterns back toward a healthier, younger profile

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Pharmacists should also ensure that patients are not taking any medicines that can adversely affect the liver, check for any potential interactions and monitor the pharmacological therapy, as adverse effects of copper chelation can potentially worsen symptoms[6]

Oral B12 (50150 g daily) may be appropriate for dietary deficiency without neurological involvement, but intramuscular hydroxocobalamin injections remain first-line treatment in the UK for patients with nerve symptoms or malabsorption conditions