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Specificity is also high, as healthy individuals do not appear to exhibit detectable P-SYN aggregates in cutaneous nerves [550, 551], though some clinical features alone may distinguish these patients from controls

Once activated, platelets secrete various immunomodulatory and microbicidal factors stored in their alpha-granules, including defensins, thrombocidins, kinocidins, and other antimicrobial peptides (85)

Tiano L, Padella L, Carnevali P, Gabrielli O, Bruge F, Principi F, Littarru GP (2008) Coenzyme Q10 and oxidative imbalance in Down syndrome: biochemical and clinical aspects

Convergence of plasma metabolomics and proteomics analysis to discover signatures of high-grade serous ovarian cancer