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De Benedetti, F, et al

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Chronic hyperglycemia, inflammation, and altered GH pulsatility can shift IGF-1 concentrations and tissue sensitivity

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Enhances muscle volume and tone Speeds recovery between workouts Helps preserve lean mass in aging adults 2

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A diagnosis of GSSD was finally made based on intractable metabolic acidosis, jaundice, hemolytic anemia, hyperbilirubinemia, massive 5-oxoprolinuria, and the presence of compound heterozygous variants in GSS

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