Moreover, L-Carnitine suppressed genes responsible for protein degradation in skeletal muscle [17] and decreased muscle RING-finger protein-1 ( MuRF1 ) and ubiquitin-protein conjugates, involved in protein catabolism, as well as increases the levels of IGF-1 and Akt1, two upstream elements in the mammalian target of rapamycin (mTOR), the main driver of protein anabolism [18]
When tested for episodic memory, subjects given a placebo prior to their THC administration showed a significant impairment while those given CBD performed on par with the control group given no THC, thus highlighting CBDs ability to prevent drug-induced memory dysfunction
Mulder GD, Patt LM, Sanders L, Rosenstock J, Altman MI, Hanley ME, Duncan GW
However, the translation of these findings into human applications remains challenging