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By employing the hypergeometric distribution, the probability of a frequency greater than k under completely random conditions was calculated using the following formula: p=1i=0k1p(i|n,m,N) where, p(i|n,m,N)=n!(Nn)!m!(Nm)!(ni)!i!(nm)!(Nnm+i)!N

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Hierarchical structure of the intervertebral disc

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For parametric statistics, we used the MannWhitney U test to compare the difference between groups

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