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One potential downside of sibling comparison studies is that they eliminate potential mediators shared between families that interact with acetaminophen [31]

performed transcriptomic profiling which demonstrated that Pterostilbene influenced the expression of genes related to sulfur metabolism by downregulating six genes (ECM17, MET3, MET14, MET16, MET10, and MET6) that encode enzyme regulating methionine biosynthesis (23)