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The primary objective of this study is to elucidate the neurotoxic effects of microplastics and their potential biological mechanisms, as well as to provide new insights and recommendations for future research in this domain

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Treatment of mutant lysates or supernatants with the reducing agent DTT (dithiothreitol) collapsed practically all the protein to monomeric size, suggesting that disulfide bonds, either intramolecular or intermolecular, are required for observation of multimers and larger species on denaturing sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE)

doi: 10.1016/s0891-5849(00)00246-x