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Andrew Huberman: Interesting

One prevailing model of metallochaperone function holds that the association between a metalated donor and an apoprotein acceptor occurs such that the donor metal complex is in close physical proximity to the empty client metal binding site, allowing client metal ligands to invade the first coordination shell of the donor metal complex, and initiate a ligand exchange process

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For instance, copper deprivation contributes to neogenesis of alpha and beta cells in the pancreatic ducts of diabetic rats [ 42 ]