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While biotin deficiency is relatively uncommon, individuals with certain metabolic conditions, those taking long-term medications such as anticonvulsants, or patients with poor nutritional absorption may benefit from intramuscular administration

For patients aged 50 years and older, recommended screening should include age-appropriate investigations in accordance with prevailing clinical practice guidelinessuch as colonoscopy for colorectal cancer, mammography for breast cancer, and cervical cytology or HPV testing as indicated

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