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PLA2G2F is a transcriptional target of PPARG and mediates the ferroptosis-inhibitory function of PPARG Given that PLA2G2F is a lipid-modifying enzyme, we hypothesized that its expression may be regulated by lipid metabolism-related transcription factors

Applying the modified Response Evaluation Criteria in Solid Tumors (mRECIST), we observed that patients with higher intracellular GSH levels responded worse to neoadjuvant chemotherapy, as indicated by MRI scans, than those with lower intracellular GSH levels (Fig