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A., Warden, C

Still, the normal, booster-treated or disease-related levels of NADs or glutathiones are not well known in humans

In addition, spatiotemporal ribonucleic acid-sequencing (RNA-seq) analyses in the mouse brain (N = 15 ROIs, seven age groups) further demonstrate region-specific (a) expression of Gss , Gclc and Gclm , three genes encoding enzymes involved in GSH synthesis, at a single time point, as well as (b) change in the expression level of these genes with age, with examples that include age-related increases of Gclc and Gclm in the hypothalamus and medulla, respectively (Hahn et al., 2022, Spatiotemporal Brain Map, 000)

astrocytes are not overtly damaged and maintain their interactions with local neurones, synapses, oligodendrocytes and vascular cells