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There have been more than 120 coffee species discovered so far, but only two of them, Coffea arabica (Arabica) and Coffea canephora (Robusta), supply 99% of the world's coffee needs (Angeloni et al., 2021

J Biol Chem 275:1325913265 Brandsma D, Kerklaan BM, Diras V, Altintas S, Anders CK, Ballester MA, Gelderblom H, Soetekouw PMMB, Gladdines W, Lonnqvist F et al (2014) Phase 1/2a study of glutathione pegylated liposomal doxorubicin (2b3-101) in patients with brain metastases (BM) from solid tumors or recurrent high grade gliomas (HGG)

The PPP supplies the RBC with NADPH to maintain the reduced state of glutathione

Thus it has been suggested that the administration of ascorbic acid should be considered for the treatment of acute paracetamol intoxication