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Metabolism of exogenous S-adenosylmethionine in isolated rat hepatocyte suspensions: methylation of plasma-membrane phospholipids without intracellular uptake

In in vivo experiments, using a mouse liver injury model, it was shown that oral administration of SC (which activates AMPK) could alleviate liver damage mediated by acute acetaminophen (by enhancing oxidative stress and increasing cell injury), exerting antioxidant effects (97)

Int J Biochem Cell Biol 61:7280

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