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A randomized controlled trial in 167 older adults (50 years) found two-year supplementation with vitamin B 12 (10 g/day), along with folic acid (200 g/day), vitamin B6 (10 mg/day), riboflavin (5 mg/day), and vitamin D (10 g/day), had no effect on bone mineral density (total hip, femoral neck, or lumbar spine) compared to the control group only receiving vitamin D (10 g/day ) (116)

Ampoule openers available on request We recommend our B12 Methylcobalamin are injected into the thigh

One study reported that vitamin B12 deficiency was associated with twice the risk of severe depression (4)

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