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We explore simple reactions involving single molecule additions to a nucleophilic side chain of proteins and complex reactions involving multiple electrophilic centers on a single molecule or involving more than one electrophilic molecule as well as the generation of reactive molecules from the interaction with cellular detoxification mechanisms

Several studies using non-invasive physiological markers, such as reduced ABR wave-I amplitude, suggest an association between cochlear synaptopathy and tinnitus, particularly in individuals with normal audiograms 11,43,61,62

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10.1016/S0022-3956(96)00025-8 J