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This blog explores the role of L-Glutathione in brain health, focusing on its antioxidant protection and support for cognitive function

Accessed October 25 th , 2021

Interestingly, a substitution at position -11 (T G) has been found in the pyrimidine-rich region of the splice acceptor site of intron 2, resulting in the activation of a cryptic splice acceptor site at position -70/-69 and consequently in the insertion of 69 nucleotides (corresponding to 23 additional amino acid residues) in the mRNA between exons 2 and 3 (302)

This is an interesting proposition since a previous study demonstrated that skin ER abundance is not altered by menopause, while dermal ER expression declined by 15% after menopause, 110 suggesting a decline in estrogen hormone action