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Gonzlez-Royo et al., 2016)

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In the livers of TLR4 knock-out mice there is reduced inflammation even in the presence of hepatic steatosis suggesting that Kupffer cell TLR4 is important in hepatic inflammatory responses to excess FFA loading

Rosetta calculations Several specialized protocols within the Rosetta software suite were employed to evaluate the impact of pAcF mutations on protein affinity maturation and stability