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Impairment of complex I leads to increased ROS production and decreased ATP synthesis, contributing to neuronal energy deficits and cell death [161]

Several neurocognitive peptides have shown memory and cognition effects in animal models and small human studies, primarily through pathways involving BDNF (brain-derived neurotrophic factor), nerve growth factor, and synaptic plasticity

Thus, the levels of GSH, GSSG and GSP1-1 were determined after incubation of intact erythrocytes with t-BOOH, a well-known trigger of oxidative stress

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