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POR is widely expressed in the endoplasmic reticulum and donates electrons from nicotinamide adenine dinucleotide phosphate (NADPH) to cytochrome P450 (CYPs) and other proteins[30]

Selenium, in particular, may enhance the activity of glutathione peroxidase, an enzyme that helps mitigate oxidative stress, which is linked to various chronic health conditions [1]

In this review, we provide a comprehensive overview of recent advances in unraveling the tug-of-war of glutamine metabolism between cancer and immune cells and explore potential applications of basic science discoveries in the clinical setting

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