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In this study, we investigate the potential of targeting Pf GR with conventional antimalarials and dual drugs combining aminoquinoline derivatives with GR inhibitors, which reveal promising interactions between Pf GR and studied drugs

Recently, by using the SPEAC technique with co-culture of cells in drops and CRISPR-Cas induced genetic manipulation, Wheeler and collaborators (153) identified the amphegulinIL33-ST2 pathway as another communication mechanism between microglia and astrocytes, relevant to the pathogenesis of MS

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DOI: 10.1186/s12985-015-0398-x 22