L., & Dover, J

Edema primarily is due to direct trauma from the needlelike crystals and, to a lesser extent, by other plant toxins (eg, bradykinins, enzymes) Symptoms: Depending on the mode of contact (skin, eye or oral): local skin erythema and/or edema (typical of a contact dermatitis ) due to contact with plant sap or juices Keratoconjunctivitis and corneal abrasions after contact with plant material, edema, erythema, bullae, and local inflammation of mouth and oral mucosa after contact Esophagitis, slurred or unintelligible speech, laryngeal edema (with sufficient contact) Superficial necrosis developing days after initial contact Treatment: Decontaminate mouth, eye, and skin by physically removing all plant material Treat eye and skin exposure with copious water irrigation Acetaminophen for pain control Antihistamines (diphenhydramine) Notes: Plant exposures are some of the most frequent poisonings reported to poison control centers Exposures to plants containing oxalate crystals, such as Philodendron and Dieffenbachia, are among the most common toxic plant exposures reported in the US References: Olson KR (2007): Poisoning & Drug Overdose

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No-DAC leans toward transient effects shared with short-pulse sermorelin (brief flushing, vivid dreams)