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The resulting suspensions were used for antioxidant enzyme assays in the respective organelles

If these ROS overwhelm the cellular antioxidant response, cell death and tissue necrosis occurs, resulting in severe hepatotoxicity that can lead to death 6

doi: 10.1073/pnas.89.6.2394 112 PuD.ZhaoY.ChenJ.SunY.LvA.ZhuS.et al