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Trohman, P.S

Melanie Avalon: Yeah, with the cyclodextrin, because they do talk in that paper about the possibly potential benefits of it as well, when you chose that compound, did you anticipate it having any other benefits, or was it more about just the mechanism of getting it into the cells

ECs were seeded in 96-well plates at a density of 3,000 cells/well (six replicate wells for each condition), followed by treatment with IL-1 (0, 1, 10, 100, 200, 500 and 1,000 ng/ml), ferrostatin-1 (0, 1, 10, 50, 100 and 200 M) or erastin (0, 1, 5, 10, 50, 100 M) alone for 24, 48, 72 h at 37C