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Pregnancy and lactation Daily iodine requirements are significantly increased in pregnant and breastfeeding women because of (1) the increased thyroid hormone production and transfer to the embryo/fetus in early pregnancy before the fetal thyroid gland becomes functional, (2) iodine transfer to the fetus during late gestation, (3) increased urinary iodine excretion, and (4) iodine transfer to the infant via breast milk (see also The RDA) (14, 21)

Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy

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Harm Reduction Journal 2 :18