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Research protocols show significant improvement in survival compared to chemotherapy alone in preclinical melanoma models, providing researchers with frameworks for studying "one-two punch" strategies that combine senolytic and targeted cancer therapies

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However, the foundational mechanism paper (Benoist et al., 2014 in J Pharmacol Exp Ther) establishing Dihexas HGF/c-Met pathway activation was formally retracted in April 2025 after being flagged since 2021

As a strong antioxidant, it fights oxidative stress which can help fight autoimmune diseases and reduce the risk of illness