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For example, a qualitative study on individuals with schizophrenia undergoing rehabilitation reported that they smoked out of boredom (Lucksted Reference Lucksted, Dixon and Sembly2000)

Although it could take longer to reach the nicotine-free dream, the health benefits of quitting are huge

BaP downregulates the activity of the Nrf2 inhibitory protein, kelch-like ECH-associated protein 1( Keap1 ), which prevents the proteasomal degradation of Nrf2 and promotes its translocation to the nucleus, where it binds to the enhancer ARE in DNA, leading to the transcription of the AOEs 58,59

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