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This copper-binding characteristic is central to the compounds biochemical identity

It is known that trimethoprim on its own can cause type 1 allergy (anaphylaxis) and StevensJohnson syndrome / toxic epidermal necrolysis

Try an online search, search forum posts or submit FOI to ICB/Health Board asking which B12 deficiency guidelines they are using and for a link to or copy of them

Furthermore any consideration of the protective action of UA in the central nervous system needs to be seen in the light of its well-established contributary role in the development of peripheral cardiovascular and metabolic diseases 2,3