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During thymic development of nTregs, the CNS2 region undergoes nearly complete DNA demethylation, which ensures the heritable stability of Foxp3 expression

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IGF-1 LR3 is one of the more potent activators of this process in the peptide space

doi: 10.1039/c9fo01014a Summary Keywords gastric cancer, oxidative stress, signaling pathways, pathophysiology, therapeutic targets Citation Liu Y, Shi Y, Han R, Liu C, Qin X, Li P and Gu R (2023) Signaling pathways of oxidative stress response: the potential therapeutic targets in gastric cancer