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The conversation spans three main areas: drugs for geroprotection (including GLP-1 agonists, SGLT2 inhibitors, methylene blue, and telomere-lengthening supplements), the use of low-dose aspirin for cardiovascular disease prevention, and strategies to improve muscle mass through optimal protein intake and follistatin gene therapy

Hoffmann sign A physical examination finding comprising involuntary flexion of the thumb and/or index finger when the examiner flicks the middle fingernail down