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525,526 Huntingtons disease (HD) HD, also known as Huntingtons chorea (Huntingtons chorea), is an autosomal dominant hereditary neurodegenerative disorder that has a tremendous devastating effect on patients and their families, characterized by chorea-like movements, cognitive decline and psychotic-like symptoms

Significant differential metabolites in the three comparisons were PE-NMe2 (20:2(11Z,14Z)/15:0), PC (22:2(13Z,16Z)/12:0), L-Alloisoleucine, PS (O-18:0/13:0), Photinus Luciferin, 5beta-Cholestan-3alpha,4alpha,11beta,12beta,21-Pentol-3,21-Disulfate, Ixocarpanolide, 2-Piperidinone, PS [(18:2(9Z,12Z)/22:5(4Z,7Z,10Z

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even if peptide mechanisms prove effective in humans, reversal would likely require sustained treatment and would be limited to veins with repairable (not completely destroyed) architecture